SCOPe 2.08: Domain d2iyra_: 2iyr A:

Lineage for d2iyra_ (2iyr A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.2: Shikimate kinase (AroK) [52566] (2 proteins)
   similar to the nucleotide/nucleoside kinases but acts on different substrate
   automatically mapped to Pfam PF01202

6. Protein automated matches [190331] (1 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [187153] (10 PDB entries)

8. Domain d2iyra_: 2iyr A: [137807]
   automated match to d1l4ua_
   complexed with skm

Details for d2iyra_

PDB Entry: 2iyr, 1.98 Å

PDB Description: shikimate kinase from mycobacterium tuberculosis in complex with shikimate

PDB Compounds: (A:) Shikimate kinase

SCOPe Domain Sequences for d2iyra_:

Sequence, based on SEQRES records:

>d2iyra_ c.37.1.2 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrlqvps

Sequence, based on observed residues (ATOM records):

>d2iyra_ c.37.1.2 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntagpdra
ekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrlqvps

Timeline for d2iyra_:

• d2iyra_ first appeared in SCOP 1.73, called d2iyra1
  
• d2iyra_ appears in SCOPe 2.07