SCOP 1.73: Domain d2iwsa1: 2iws A:2-214

Lineage for d2iwsa1 (2iws A:2-214)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (1 protein)

6. Protein HSP90 [55876] (3 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55877] (15 PDB entries)

8. Domain d2iwsa1: 2iws A:2-214 [137756]
   automatically matched to d1ah8b_
   complexed with np4

Details for d2iwsa1

PDB Entry: 2iws, 2.7 Å

PDB Description: radicicol analogues bound to the atp site of hsp90

PDB Compounds: (A:) ATP-dependent molecular chaperone hsp82

SCOP Domain Sequences for d2iwsa1:

Sequence, based on SEQRES records:

>d2iwsa1 d.122.1.1 (A:2-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
lfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfg
vgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddq
leyleekrikevikrhsefvaypiqlvvtkeve

Sequence, based on observed residues (ATOM records):

>d2iwsa1 d.122.1.1 (A:2-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
asetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepd
lfiritpkpeqkvleirdsgigmtkaelinnlgtigtkafmealsagadvsmigqfgvgf
yslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqley
leekrikevikrhsefvaypiqlvvtkeve

Timeline for d2iwsa1:

• d2iwsa1 is new in SCOP 1.73
  
• d2iwsa1 appears in SCOP 1.75
  
• d2iwsa1 appears in the current release, SCOPe 2.08, called d2iwsa_