Lineage for d2iw9b1 (2iw9 B:176-309)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2718075Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2718076Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2718077Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. 2718090Protein Cyclin A [47956] (2 species)
  7. 2718126Species Human (Homo sapiens) [TaxId:9606] [47957] (89 PDB entries)
    Uniprot P20248 175-432
  8. 2718143Domain d2iw9b1: 2iw9 B:176-309 [137748]
    Other proteins in same PDB: d2iw9a2, d2iw9a3, d2iw9c2, d2iw9c3
    automated match to d1oi9b1
    complexed with 4sp, mg, sgm

Details for d2iw9b1

PDB Entry: 2iw9 (more details), 2 Å

PDB Description: structure of human thr160-phospho cdk2-cyclin a complexed with a bisanilinopyrimidine inhibitor
PDB Compounds: (B:) Cyclin-A2

SCOPe Domain Sequences for d2iw9b1:

Sequence, based on SEQRES records: (download)

>d2iw9b1 a.74.1.1 (B:176-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
pdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhla
vnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrme
hlvlkvltfdlaap

Sequence, based on observed residues (ATOM records): (download)

>d2iw9b1 a.74.1.1 (B:176-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
pdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhla
vnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyittytkkqvlrmehl
vlkvltfdlaap

SCOPe Domain Coordinates for d2iw9b1:

Click to download the PDB-style file with coordinates for d2iw9b1.
(The format of our PDB-style files is described here.)

Timeline for d2iw9b1: