SCOP 1.73: Domain d2iw8d2: 2iw8 D:309-432

Lineage for d2iw8d2 (2iw8 D:309-432)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (3 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (4 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [47958] (19 PDB entries)

8. Domain d2iw8d2: 2iw8 D:309-432 [137747]
   automatically matched to d1vin_2
   complexed with 4sp, sgm; mutant

Details for d2iw8d2

PDB Entry: 2iw8, 2.3 Å

PDB Description: structure of human thr160-phospho cdk2-cyclin a f82h-l83v-h84d mutant with an o6-cyclohexylmethylguanine inhibitor

PDB Compounds: (D:) Cyclin-A2

SCOP Domain Sequences for d2iw8d2:

Sequence; same for both SEQRES and ATOM records:

>d2iw8d2 a.74.1.1 (D:309-432) Cyclin A {Cow (Bos taurus) [TaxId: 9913]}
ptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsviagaafhlalytvt
gqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyknskyhgvsllnppe
tlnl

Timeline for d2iw8d2:

• d2iw8d2 is new in SCOP 1.73
  
• d2iw8d2 appears in SCOP 1.75
  
• d2iw8d2 appears in the current release, SCOPe 2.08