Lineage for d2iw6d1 (2iw6 D:178-309)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2003386Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2003387Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2003388Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. 2003401Protein Cyclin A [47956] (2 species)
  7. 2003437Species Human (Homo sapiens) [TaxId:9606] [47957] (81 PDB entries)
    Uniprot P20248 175-432
  8. 2003578Domain d2iw6d1: 2iw6 D:178-309 [137742]
    Other proteins in same PDB: d2iw6a1, d2iw6a2, d2iw6c2, d2iw6c3
    automated match to d1oiub1
    complexed with mg, qq2, sgm

Details for d2iw6d1

PDB Entry: 2iw6 (more details), 2.3 Å

PDB Description: structure of human thr160-phospho cdk2-cyclin a complexed with a bisanilinopyrimidine inhibitor
PDB Compounds: (D:) Cyclin-A2

SCOPe Domain Sequences for d2iw6d1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2iw6d1 a.74.1.1 (D:178-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
yhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhlavn
yidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrmehl
vlkvltfdlaap

SCOPe Domain Coordinates for d2iw6d1:

Click to download the PDB-style file with coordinates for d2iw6d1.
(The format of our PDB-style files is described here.)

Timeline for d2iw6d1: