SCOPe 2.08: Domain d2ispa1: 2isp A:10-91

Lineage for d2ispa1 (2isp A:10-91)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.60: SAM domain-like [47768] (17 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.6: DNA polymerase beta, N-terminal domain-like [47802] (2 families)
   contains one classic and one pseudo HhH motifs

5. Family a.60.6.1: DNA polymerase beta, N-terminal domain-like [47803] (3 proteins)

6. Protein DNA polymerase beta, N-terminal (8 kD)-domain [47804] (2 species)
   topologically similar to the second domain

7. Species Human (Homo sapiens) [TaxId:9606] [47805] (145 PDB entries)
   Uniprot P06746

8. Domain d2ispa1: 2isp A:10-91 [137609]
   Other proteins in same PDB: d2ispa2, d2ispa3
   automated match to d1tv9a1
   protein/DNA complex; complexed with cl, ggh, mg, na

Details for d2ispa1

PDB Entry: 2isp, 2.2 Å

PDB Description: Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate

PDB Compounds: (A:) Polymerase (DNA directed), beta

SCOPe Domain Sequences for d2ispa1:

Sequence; same for both SEQRES and ATOM records:

>d2ispa1 a.60.6.1 (A:10-91) DNA polymerase beta, N-terminal (8 kD)-domain {Human (Homo sapiens) [TaxId: 9606]}
tlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpgvgtki
aekideflatgklrklekirqd

Timeline for d2ispa1:

• d2ispa1 first appeared in SCOP 1.73
  
• d2ispa1 appears in SCOPe 2.07