Lineage for d2inqa1 (2inq A:1-159)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 707730Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 707731Superfamily c.71.1: Dihydrofolate reductase-like [53597] (2 families) (S)
  5. 707732Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)
  6. 707752Protein Dihydrofolate reductase, prokaryotic type [53599] (6 species)
  7. 707755Species Escherichia coli [TaxId:562] [53600] (45 PDB entries)
  8. 707812Domain d2inqa1: 2inq A:1-159 [137531]
    automatically matched to d1dre__
    complexed with mt1; mutant

Details for d2inqa1

PDB Entry: 2inq (more details), 2.2 Å

PDB Description: neutron crystal structure of escherichia coli dihydrofolate reductase bound to the anti-cancer drug, methotrexate
PDB Compounds: (A:) dihydrofolate reductase

SCOP Domain Sequences for d2inqa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2inqa1 c.71.1.1 (A:1-159) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}

SCOP Domain Coordinates for d2inqa1:

Click to download the PDB-style file with coordinates for d2inqa1.
(The format of our PDB-style files is described here.)

Timeline for d2inqa1: