SCOPe 2.07: Domain d2imbb2: 2imb B:1-416

Lineage for d2imbb2 (2imb B:1-416)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (29 PDB entries)
   Uniprot P10845 1-419

8. Domain d2imbb2: 2imb B:1-416 [137512]
   Other proteins in same PDB: d2imba3, d2imbb3
   automated match to d1xtga_
   complexed with ahl, zn

Details for d2imbb2

PDB Entry: 2imb, 2.41 Å

PDB Description: clostridium botulinum neurotoxin serotype a light chain inhibited by l-arginine hydroxamate

PDB Compounds: (B:) Botulinum neurotoxin A light-chain

SCOPe Domain Sequences for d2imbb2:

Sequence, based on SEQRES records:

>d2imbb2 d.92.1.7 (B:1-416) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdtftnpeegdln
pppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwgg
stidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngy
gstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpn
rvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnka
ksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkv
lnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftkl

Sequence, based on observed residues (ATOM records):

>d2imbb2 d.92.1.7 (B:1-416) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipnmqpvkafkihnkiwviperdtftnpeegdlnppv
syydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvi
dtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngygstqyirfsp
dftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpnrvevsfeelr
tfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttaslqymknvfkekylls
edtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvny
tiydgfnlrntnlaanfngqnteinnmnftkl

Timeline for d2imbb2:

• d2imbb2 first appeared in SCOP 1.73, called d2imbb1
  
• d2imbb2 appears in SCOPe 2.06
  
• d2imbb2 appears in the current release, SCOPe 2.08