SCOPe 2.08: Domain d2imba2: 2imb A:1-418

Lineage for d2imba2 (2imb A:1-418)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (29 PDB entries)
   Uniprot P10845 1-419

8. Domain d2imba2: 2imb A:1-418 [137511]
   Other proteins in same PDB: d2imba3, d2imbb3
   automated match to d1xtga_
   complexed with ahl, zn

Details for d2imba2

PDB Entry: 2imb, 2.41 Å

PDB Description: clostridium botulinum neurotoxin serotype a light chain inhibited by l-arginine hydroxamate

PDB Compounds: (A:) Botulinum neurotoxin A light-chain

SCOPe Domain Sequences for d2imba2:

Sequence, based on SEQRES records:

>d2imba2 d.92.1.7 (A:1-418) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdtftnpeegdln
pppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwgg
stidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngy
gstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpn
rvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnka
ksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkv
lnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklkn

Sequence, based on observed residues (ATOM records):

>d2imba2 d.92.1.7 (A:1-418) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipvkafkihnkiwviperdtftnpeegdlnppvpvsy
ydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelkvidt
ncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngygstqyirfspdf
tfgfeeslagkfatdpavtlahelihaghrlygiainpnrvfkevsfeelrtfgghdakf
idslqenefrlyyynkfkdiastlnkaksivgaslqymknvfkekyllsedtsgkfsvdk
lkfdklykmlteiytednfvkffkvlnrktylnfdkavfkinivpkvnytiydgfnlrnt
nlaanfngqnteinnmnftklkn

Timeline for d2imba2:

• d2imba2 first appeared in SCOP 1.73, called d2imba1
  
• d2imba2 appears in SCOPe 2.07