SCOPe 2.08: Domain d2ilpa2: 2ilp A:1-419

Lineage for d2ilpa2 (2ilp A:1-419)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.7: Clostridium neurotoxins, catalytic domain [55512] (2 proteins)

6. Protein Botulinum neurotoxin [55513] (4 species)

7. Species Clostridium botulinum, serotype A [TaxId:1491] [55514] (29 PDB entries)
   Uniprot P10845 1-419

8. Domain d2ilpa2: 2ilp A:1-419 [137496]
   Other proteins in same PDB: d2ilpa3, d2ilpb3
   automated match to d1xtga_
   complexed with gb5, po4, zn

Details for d2ilpa2

PDB Entry: 2ilp, 1.9 Å

PDB Description: clostridium botulinum serotype a light chain inhibited by 4- chlorocinnamic hydroxamate

PDB Compounds: (A:) Botulinum neurotoxin A light-chain

SCOPe Domain Sequences for d2ilpa2:

Sequence, based on SEQRES records:

>d2ilpa2 d.92.1.7 (A:1-419) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipnvgqmqpvkafkihnkiwviperdtftnpeegdln
pppeakqvpvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwgg
stidtelkvidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngy
gstqyirfspdftfgfeeslevdtnpllgagkfatdpavtlahelihaghrlygiainpn
rvfkvntnayyemsglevsfeelrtfgghdakfidslqenefrlyyynkfkdiastlnka
ksivgttaslqymknvfkekyllsedtsgkfsvdklkfdklykmlteiytednfvkffkv
lnrktylnfdkavfkinivpkvnytiydgfnlrntnlaanfngqnteinnmnftklknf

Sequence, based on observed residues (ATOM records):

>d2ilpa2 d.92.1.7 (A:1-419) Botulinum neurotoxin {Clostridium botulinum, serotype A [TaxId: 1491]}
mqfvnkqfnykdpvngvdiayikipqmqpvkafkihnkiwviperdtftnpeegdlnppv
pvsyydstylstdnekdnylkgvtklferiystdlgrmlltsivrgipfwggstidtelk
vidtncinviqpdgsyrseelnlviigpsadiiqfecksfghevlnltrngygstqyirf
spdftfgfeeslevnpllgagkfatdpavtlahelihaghrlygiainpnrvfkevsfee
lrtfgghdakfidslqenefrlyyynkfkdiastlnkaksivgttaslqymknvfkekyl
lsedtsgkfsvdklkfdklykmlteiytednfvkffkvlnrktylnfdkavfkinivpkv
nytiydgfnlrntnlaanfngqnteinnmnftklknf

Timeline for d2ilpa2:

• d2ilpa2 first appeared in SCOP 1.73, called d2ilpa1
  
• d2ilpa2 appears in SCOPe 2.07