SCOP 1.73: Domain d2ii0a1: 2ii0 A:566-1045

Lineage for d2ii0a1 (2ii0 A:566-1045)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (1 protein)

6. Protein Son of sevenless protein homolog 1 (sos-1) [48368] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48369] (9 PDB entries)

8. Domain d2ii0a1: 2ii0 A:566-1045 [137425]
   automatically matched to d1nvus_

Details for d2ii0a1

PDB Entry: 2ii0, 2.02 Å

PDB Description: Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras

PDB Compounds: (A:) Son of sevenless homolog 1

SCOP Domain Sequences for d2ii0a1:

Sequence, based on SEQRES records:

>d2ii0a1 a.117.1.1 (A:566-1045) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfvr
tflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpv
qlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiard
ngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselv
gsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqel
nnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinpp
cvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrves
dikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp

Sequence, based on observed residues (ATOM records):

>d2ii0a1 a.117.1.1 (A:566-1045) Son of sevenless protein homolog 1 (sos-1) {Human (Homo sapiens) [TaxId: 9606]}
qmrlpsadvyrfaepdseeniifegipiikagtviklierltyhmyadpnfvrtflttyr
sfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvlnv
crhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiafqsspptve
whisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeinspnll
kmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsamnssp
vyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnilktee
gnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmgnsme
keftdylfnksleieprnpkplprfpkkysyplkspgvrpsnp

Timeline for d2ii0a1:

• d2ii0a1 is new in SCOP 1.73
  
• d2ii0a1 appears in SCOP 1.75
  
• d2ii0a1 appears in the current release, SCOPe 2.08, called d2ii0a_