SCOPe 2.08: Domain d2ihza2: 2ihz A:26-412

Lineage for d2ihza2 (2ihz A:26-412)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.87: UDP-Glycosyltransferase/glycogen phosphorylase [53755] (1 superfamily)
   consists of two non-similar domains with 3 layers (a/b/a) each
   domain 1: parallel beta-sheet of 7 strands, order 3214567
   domain 2: parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.87.1: UDP-Glycosyltransferase/glycogen phosphorylase [53756] (14 families)

5. Family c.87.1.9: Sialyltransferase-like [142773] (2 proteins)
   automatically mapped to Pfam PF11477

6. Protein Alpha-2,3/2,6-sialyltransferase/sialidase [142774] (1 species)

7. Species Pasteurella multocida [TaxId:747] [142775] (12 PDB entries)
   Uniprot Q15KI8 26-412

8. Domain d2ihza2: 2ihz A:26-412 [137424]
   Other proteins in same PDB: d2ihza3
   automated match to d2ex0a1
   complexed with csf

Details for d2ihza2

PDB Entry: 2ihz, 2 Å

PDB Description: crystal structure of multifunctional sialyltransferase from pasteurella multocida with cmp-3f-neu5ac and alpha-lactose bound

PDB Compounds: (A:) alpha-2,3/2,6-sialyltransferase/sialidase

SCOPe Domain Sequences for d2ihza2:

Sequence, based on SEQRES records:

>d2ihza2 c.87.1.9 (A:26-412) Alpha-2,3/2,6-sialyltransferase/sialidase {Pasteurella multocida [TaxId: 747]}
ktitlyldpaslpalnqlmdftqnnedkthprifglsrfkipdniitqyqnihfvelkdn
rptealftildqypgnielnihlniahsvqlirpilayrfkhldrvsiqqlnlyddgsme
yvdlekeenkdisaeikqaekqlshylltgkikfdnptiaryvwqsafpvkyhflstdyf
ekaeflqplkeylaenyqkmdwtayqqltpeqqafyltlvgfndevkqslevqqakfift
gtttwegntdvreyyaqqqlnllnhftqaegdlfigdhykiyfkghprggeindyilnna
knitnipanisfevlmmtgllpdkvggvasslyfslpkekishiiftsnkqvkskedaln
npyvkvmrrlgiidesqvifwdslkql

Sequence, based on observed residues (ATOM records):

>d2ihza2 c.87.1.9 (A:26-412) Alpha-2,3/2,6-sialyltransferase/sialidase {Pasteurella multocida [TaxId: 747]}
ktitlyldpaslpalnqlmdftqnnedkthprifglsrfkipdniitqyqnihfvelkdn
rptealftildqypgnielnihlniahsvqlirpilayrfkhldrvsiqqlnlyddgsme
yvdlekeenkdisaeikqaekqlshylltgkikfdnptiaryvwqsafpvkyhflstdyf
ekaeflqplkeylaenyqkmdwtayqqltpeqqafyltlvgfndevkqslevqqakfift
gtttwegntdvreyyaqqqlnllnhftqaegdlfigdhykiyfkghprggeindyilnna
knitnipanisfevlmmtgllpdkvggvasslyfslpkekishiiftsalnnpyvkvmrr
lgiidesqvifwdslkql

Timeline for d2ihza2:

• d2ihza2 first appeared in SCOP 1.73, called d2ihza1
  
• d2ihza2 appears in SCOPe 2.07