SCOPe 2.08: Domain d2igtc2: 2igt C:1-309

Lineage for d2igtc2 (2igt C:1-309)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.51: hypothetical RNA methyltransferase [142635] (4 proteins)
   C-terminal part of Pfam PF03602; similar to (Uracil-5-)-methyltransferase (Pfam PF05958)

6. Protein Putative methyltransferase Atu0340 [142636] (1 species)
   there is no associated PUA domain; rudiment extra N-terminal subdomain

7. Species Agrobacterium tumefaciens [TaxId:358] [142637] (1 PDB entry)
   Uniprot Q8UIF7 1-309

8. Domain d2igtc2: 2igt C:1-309 [137403]
   Other proteins in same PDB: d2igta2, d2igtb3, d2igtc3
   automated match to d2igta1
   complexed with acy, fmt, gol, sam

Details for d2igtc2

PDB Entry: 2igt, 1.89 Å

PDB Description: crystal structure of the sam dependent methyltransferase from agrobacterium tumefaciens

PDB Compounds: (C:) SAM dependent methyltransferase

SCOPe Domain Sequences for d2igtc2:

Sequence, based on SEQRES records:

>d2igtc2 c.66.1.51 (C:1-309) Putative methyltransferase Atu0340 {Agrobacterium tumefaciens [TaxId: 358]}
mqrtgelpaehvpvilessgagdfhlidsgnglkleqygdyrvvrpeaqalwrplvpdrv
wqnadaiftgdtdedgmgrwrfpkealgetwplsllgveflgrftafrhvgvfpeqivhw
ewlknavetadrplkvlnlfgytgvaslvaaaagaevthvdaskkaigwakenqvlagle
qapirwicedamkfiqreerrgstydiiltdppkfgrgthgevwqlfdhlplmldicrei
lspkalglvltaysirasfysmhelmretmrgaggvvasgelvireagldgktpgrvlst
slfsrwepk

Sequence, based on observed residues (ATOM records):

>d2igtc2 c.66.1.51 (C:1-309) Putative methyltransferase Atu0340 {Agrobacterium tumefaciens [TaxId: 358]}
mqrtgelpaehvpvilessgagdfhlidsgnglkleqygdyrvvrpeaqalwrplvpdrv
wqnadaiftgddgmgrwrfpkealgetwplsllgveflgrftafrhvgvfpeqivhwewl
knavetadrplkvlnlfgytgvaslvaaaagaevthvdaskkaigwakenqvlagleqap
irwicedamkfiqreerrgstydiiltdppkfgrgthgevwqlfdhlplmldicreilsp
kalglvltaysirasfysmhelmretmrgaggvvasgelvireagldgktpgrvlstslf
srwepk

Timeline for d2igtc2:

• d2igtc2 first appeared in SCOP 1.73, called d2igtc1
  
• d2igtc2 appears in SCOPe 2.07