SCOP 1.73: Domain d2ifge1: 2ifg E:2-115

Lineage for d2ifge1 (2ifg E:2-115)

1. Root: SCOP 1.73

2. Class g: Small proteins [56992] (85 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.3: Neurotrophin [57520] (4 proteins)

6. Protein beta-Nerve growth factor [57525] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57527] (3 PDB entries)

8. Domain d2ifge1: 2ifg E:2-115 [137341]
   Other proteins in same PDB: d2ifga1, d2ifga2, d2ifga3, d2ifgb1, d2ifgb2, d2ifgb3
   automatically matched to d1wwww_
   complexed with bma, man, nag, ndg

Details for d2ifge1

PDB Entry: 2ifg, 3.4 Å

PDB Description: structure of the extracellular segment of human trka in complex with nerve growth factor

PDB Compounds: (E:) Beta-nerve growth factor

SCOP Domain Sequences for d2ifge1:

Sequence, based on SEQRES records:

>d2ifge1 g.17.1.3 (E:2-115) beta-Nerve growth factor {Human (Homo sapiens) [TaxId: 9606]}
sshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrdp
npvdsgcrgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrk

Sequence, based on observed residues (ATOM records):

>d2ifge1 g.17.1.3 (E:2-115) beta-Nerve growth factor {Human (Homo sapiens) [TaxId: 9606]}
sshpifhrgefsvcdsvsvwvgdkttatdikgkevmvlgevninnsvfkqyffetkcrdg
crgidskhwnsycttthtfvkaltmdgkqaawrfiridtacvcvlsrk

Timeline for d2ifge1:

• d2ifge1 is new in SCOP 1.73
  
• d2ifge1 appears in SCOP 1.75
  
• d2ifge1 appears in the current release, SCOPe 2.08