Lineage for d2ieha_ (2ieh A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2111568Family c.37.1.9: Motor proteins [52641] (5 protein domains)
  6. 2111709Protein automated matches [190129] (6 species)
    not a true protein
  7. 2111718Species Human (Homo sapiens) [TaxId:9606] [187145] (33 PDB entries)
  8. 2111777Domain d2ieha_: 2ieh A: [137309]
    automated match to d1q0bb_
    complexed with adp, cl, k, mg, moy, pg4

Details for d2ieha_

PDB Entry: 2ieh (more details), 2.7 Å

PDB Description: Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer
PDB Compounds: (A:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d2ieha_:

Sequence, based on SEQRES records: (download)

>d2ieha_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfga
stkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplag
iiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgv
iikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgee
lvkigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyres
kltrilqdslggrtrtsiiatispaslnleetlstleyahraknilnkpe

Sequence, based on observed residues (ATOM records): (download)

>d2ieha_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kgkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfga
stkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplag
iiprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgv
iikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgee
lvkigklnlvdlagseninqslltlgrvitalvertphvpyreskltrilqdslggrtrt
siiatispaslnleetlstleyahraknilnkpe

SCOPe Domain Coordinates for d2ieha_:

Click to download the PDB-style file with coordinates for d2ieha_.
(The format of our PDB-style files is described here.)

Timeline for d2ieha_: