SCOPe 2.06: Domain d2i9tb2: 2i9t B:339-550

Lineage for d2i9tb2 (2i9t B:339-550)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.3: Rel/Dorsal transcription factors, DNA-binding domain [81315] (7 proteins)
   automatically mapped to Pfam PF00554

6. Protein p50 subunit of NF-kappa B (NFKB), N-terminal domain [49423] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [49425] (7 PDB entries)

8. Domain d2i9tb2: 2i9t B:339-550 [137132]
   Other proteins in same PDB: d2i9ta1, d2i9ta2, d2i9ta3, d2i9tb1
   automated match to d1leib2
   protein/DNA complex

Details for d2i9tb2

PDB Entry: 2i9t, 2.8 Å

PDB Description: structure of nf-kb p65-p50 heterodimer bound to prdii element of b- interferon promoter

PDB Compounds: (B:) Nuclear factor NF-kappa-B p105 subunit

SCOPe Domain Sequences for d2i9tb2:

Sequence; same for both SEQRES and ATOM records:

>d2i9tb2 b.2.5.3 (B:339-550) p50 subunit of NF-kappa B (NFKB), N-terminal domain {Mouse (Mus musculus) [TaxId: 10090]}
gpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivqlv
tngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmtea
cirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftafl
pdstgsftrrlepvvsdaiydskapnasnlki

Timeline for d2i9tb2:

• d2i9tb2 first appeared in SCOP 1.73
  
• d2i9tb2 appears in SCOPe 2.05
  
• d2i9tb2 appears in SCOPe 2.07
  
• d2i9tb2 appears in the current release, SCOPe 2.08