SCOPe 2.08: Domain d2i60p2: 2i60 P:83-492

Lineage for d2i60p2 (2i60 P:83-492)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.172: gp120 core [56501] (1 superfamily)
   unusual fold

4. Superfamily d.172.1: gp120 core [56502] (1 family)

5. Family d.172.1.1: gp120 core [56503] (2 proteins)

6. Protein gp120 core [56504] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56505] (18 PDB entries)

8. Domain d2i60p2: 2i60 P:83-492 [137086]
   Other proteins in same PDB: d2i60h1, d2i60h2, d2i60l1, d2i60l2, d2i60m1, d2i60p3, d2i60q1, d2i60q2, d2i60r1, d2i60r2, d2i60s1
   automated match to d1g9ng_
   complexed with ipa, nag

Details for d2i60p2

PDB Entry: 2i60, 2.4 Å

PDB Description: crystal structure of [phe23]m47, a scorpion-toxin mimic of cd4, in complex with hiv-1 yu2 gp120 envelope glycoprotein and anti-hiv-1 antibody 17b

PDB Compounds: (P:) Exterior membrane glycoprotein(GP120)

SCOPe Domain Sequences for d2i60p2:

Sequence, based on SEQRES records:

>d2i60p2 d.172.1.1 (P:83-492) gp120 core {Human immunodeficiency virus type 1 [TaxId: 11676]}
evklenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
kvsfepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqlllngsla
eeeivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklkeqfgn
nktiifnpssggdpeivthsfncggeffycnstqlftwndtrklnntgrnitlpcrikqi
inmwqevgkamyappirgqircssnitgllltrdggkdtngteifrpgggdmrdnwrsel
ykykvvkie

Sequence, based on observed residues (ATOM records):

>d2i60p2 d.172.1.1 (P:83-492) gp120 core {Human immunodeficiency virus type 1 [TaxId: 11676]}
evklenvtenfnmwknnmveqmhediislwdqslkpcvkltplcvgagscntsvitqacp
kvsfepipihycapagfailkcndkkfngtgpctnvstvqcthgirpvvstqlllngsla
eeeivirsenftnnaktiivqlnesvvinctgaghcnlsktqwentleqiaiklkeqfgn
nktiifnpssggdpeivthsfncggeffycnstqlftwrnitlpcrikqiinmwqevgka
myappirgqircssnitgllltrdggkdtngteifrpgggdmrdnwrselykykvvkie

Timeline for d2i60p2:

• d2i60p2 first appeared in SCOP 1.73, called d2i60p1
  
• d2i60p2 appears in SCOPe 2.07