SCOPe 2.08: Domain d2i42a_: 2i42 A:

Lineage for d2i42a_ (2i42 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein Protein-tyrosine phosphatase YopH, catalytic domain [100952] (2 species)

7. Species Yersinia enterocolitica [TaxId:630] [52812] (20 PDB entries)

8. Domain d2i42a_: 2i42 A: [137044]
   automated match to d1qz0a_
   complexed with vo4

Details for d2i42a_

PDB Entry: 2i42, 2.2 Å

PDB Description: crystal structure of yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue

PDB Compounds: (A:) Tyrosine-protein phosphatase

SCOPe Domain Sequences for d2i42a_:

Sequence; same for both SEQRES and ATOM records:

>d2i42a_ c.45.1.2 (A:) Protein-tyrosine phosphatase YopH, catalytic domain {Yersinia enterocolitica [TaxId: 630]}
spygpearaelssrlttlrntlapatndprylqacggeklnrfrdiqcrrqtavradlna
nyiqvgntrtiacqyplqsqleshfrmlaenrtpvlavlassseianqrfgmpdyfrqsg
tygsitveskmtqqvglgdgimadmytltireagqktisvpvvhvgnwpdqtavssevtk
alaslvdqtaetkrnmyeskgssavaddsklrpvihcragvgrtaqligamcmndsrnsq
lsvedmvsqmrvqrngimvqkdeqldvliklaegqgrpllns

Timeline for d2i42a_:

• d2i42a_ first appeared in SCOP 1.73, called d2i42a1
  
• d2i42a_ appears in SCOPe 2.07