Lineage for d2i40b2 (2i40 B:310-431)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2326510Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2326511Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2326512Family a.74.1.1: Cyclin [47955] (9 proteins)
  6. 2326525Protein Cyclin A [47956] (2 species)
  7. 2326561Species Human (Homo sapiens) [TaxId:9606] [47957] (83 PDB entries)
    Uniprot P20248 175-432
  8. 2326713Domain d2i40b2: 2i40 B:310-431 [137040]
    Other proteins in same PDB: d2i40a_, d2i40c_
    automated match to d1jsub2
    complexed with blz

Details for d2i40b2

PDB Entry: 2i40 (more details), 2.8 Å

PDB Description: Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor
PDB Compounds: (B:) Cyclin-A2

SCOPe Domain Sequences for d2i40b2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2i40b2 a.74.1.1 (B:310-431) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2i40b2:

Click to download the PDB-style file with coordinates for d2i40b2.
(The format of our PDB-style files is described here.)

Timeline for d2i40b2: