SCOP 1.73: Domain d2i0ga1: 2i0g A:261-497

Lineage for d2i0ga1 (2i0g A:261-497)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

6. Protein Estrogen receptor beta [48521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48522] (15 PDB entries)

8. Domain d2i0ga1: 2i0g A:261-497 [136950]
   automatically matched to d1l2jb_
   complexed with i0g

Details for d2i0ga1

PDB Entry: 2i0g, 2.5 Å

PDB Description: benzopyrans are selective estrogen receptor beta agonists (serbas) with novel activity in models of benign prostatic hyperplasia

PDB Compounds: (A:) Estrogen receptor beta

SCOP Domain Sequences for d2i0ga1:

Sequence, based on SEQRES records:

>d2i0ga1 a.123.1.1 (A:261-497) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
dalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfv
elslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdml
lattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwv
iaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlna

Sequence, based on observed residues (ATOM records):

>d2i0ga1 a.123.1.1 (A:261-497) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
dalspeqlvltlleaepphvlisrpasmmmsltkladkelvhmiswakkipgfvelslfd
qvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmllattsr
frelklqhkeylcvkamillnssmyplvssrklahllnavtdalvwviaksgissqqqsm
rlanllmllshvrhasnkgmehllnmkvpvydlllemlna

Timeline for d2i0ga1:

• d2i0ga1 is new in SCOP 1.73
  
• d2i0ga1 appears in SCOP 1.75
  
• d2i0ga1 appears in the current release, SCOPe 2.08, called d2i0ga_