SCOPe 2.07: Domain d2hzna2: 2hzn A:229-502

Lineage for d2hzna2 (2hzn A:229-502)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Abelsone tyrosine kinase (abl) [56166] (2 species)
   PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56167] (9 PDB entries)

8. Domain d2hzna2: 2hzn A:229-502 [136915]
   Other proteins in same PDB: d2hzna3
   automated match to d1opjb_
   complexed with kin

Details for d2hzna2

PDB Entry: 2hzn, 2.7 Å

PDB Description: abl kinase domain in complex with nvp-afg210

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2hzna2:

Sequence, based on SEQRES records:

>d2hzna2 d.144.1.7 (A:229-502) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
spnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaa
vmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqis
sameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtap
eslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekv
yelmracwqwnpsdrpsfaeihqafetmfqessi

Sequence, based on observed residues (ATOM records):

>d2hzna2 d.144.1.7 (A:229-502) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
spnydkwemertditmkhklgggevyegvwkkysltvavktldtmeveeflkeaavmkei
khpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqissamey
lekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslay
nkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmr
acwqwnpsdrpsfaeihqafetmfqessi

Timeline for d2hzna2:

• d2hzna2 first appeared in SCOP 1.73, called d2hzna1
  
• d2hzna2 appears in SCOPe 2.06
  
• d2hzna2 appears in the current release, SCOPe 2.08