Lineage for d2huwb_ (2huw B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2530460Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2530461Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2530462Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 2530616Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)
  7. 2530617Species Human (Homo sapiens) [TaxId:9606] [55564] (38 PDB entries)
  8. 2530650Domain d2huwb_: 2huw B: [136780]
    automated match to d1fhs__
    complexed with po4, yvn

Details for d2huwb_

PDB Entry: 2huw (more details), 1.9 Å

PDB Description: x-ray crystal structure of the grb2 sh2 domain complexed to a constrained and cyclopropane-derived ligand
PDB Compounds: (B:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d2huwb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2huwb_ d.93.1.1 (B:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
kphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdga
gkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieq

SCOPe Domain Coordinates for d2huwb_:

Click to download the PDB-style file with coordinates for d2huwb_.
(The format of our PDB-style files is described here.)

Timeline for d2huwb_: