Lineage for d2huwa_ (2huw A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2206459Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices
  4. 2206460Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 2206461Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 2206615Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)
  7. 2206616Species Human (Homo sapiens) [TaxId:9606] [55564] (35 PDB entries)
  8. 2206627Domain d2huwa_: 2huw A: [136779]
    automated match to d1fhs__
    complexed with po4, yvn

Details for d2huwa_

PDB Entry: 2huw (more details), 1.9 Å

PDB Description: x-ray crystal structure of the grb2 sh2 domain complexed to a constrained and cyclopropane-derived ligand
PDB Compounds: (A:) Growth factor receptor-bound protein 2

SCOPe Domain Sequences for d2huwa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2huwa_ d.93.1.1 (A:) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
mkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdg
agkyflwvvkfnslnelvdyhrstsvsrnqqiflrdieqvp

SCOPe Domain Coordinates for d2huwa_:

Click to download the PDB-style file with coordinates for d2huwa_.
(The format of our PDB-style files is described here.)

Timeline for d2huwa_: