SCOPe 2.06: Domain d2hsha_: 2hsh A:

Lineage for d2hsha_ (2hsh A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

4. Superfamily c.47.1: Thioredoxin-like [52833] (24 families)

5. Family c.47.1.1: Thioltransferase [52834] (16 proteins)

6. Protein Thioredoxin [52835] (16 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52842] (30 PDB entries)

8. Domain d2hsha_: 2hsh A: [136724]
   automated match to d1erv__
   complexed with po4; mutant

Details for d2hsha_

PDB Entry: 2hsh, 1.35 Å

PDB Description: crystal structure of c73s mutant of human thioredoxin-1 oxidized with h2o2

PDB Compounds: (A:) thioredoxin

SCOPe Domain Sequences for d2hsha_:

Sequence; same for both SEQRES and ATOM records:

>d2hsha_ c.47.1.1 (A:) Thioredoxin {Human (Homo sapiens) [TaxId: 9606]}
mvkqiesktafqealdaagdklvvvdfsatwcgpckmikpffhslsekysnviflevdvd
dcqdvasecevksmptfqffkkgqkvgefsgankekleatinelv

Timeline for d2hsha_:

• d2hsha_ first appeared in SCOP 1.73, called d2hsha1
  
• d2hsha_ appears in SCOPe 2.05
  
• d2hsha_ appears in SCOPe 2.07
  
• d2hsha_ appears in the current release, SCOPe 2.08