Lineage for d2hlfd1 (2hlf D:1-105)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2021374Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2021375Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2021376Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2022563Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2023085Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88528] (40 PDB entries)
    Uniprot P04940 # KV6F_MOUSE IG KAPPA CHAIN V-VI REGION NQ2-17.4.1
  8. 2023141Domain d2hlfd1: 2hlf D:1-105 [136566]
    Other proteins in same PDB: d2hlfa1, d2hlfb1, d2hlfd2, d2hlff2
    automatically matched to d1dqdl1
    complexed with br; mutant

Details for d2hlfd1

PDB Entry: 2hlf (more details), 3.3 Å

PDB Description: structure of the escherichis coli clc chloride channel y445e mutant and fab complex
PDB Compounds: (D:) Fab fragment, light chain

SCOPe Domain Sequences for d2hlfd1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hlfd1 b.1.1.1 (D:1-105) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
divltqspaimsaapgdkvtmtcsasssvsyihwyqqksgtspkrwiydtskltsgvpvr
fsgsgsgtsysltintmeaedaatyycqqwsshpqtfgggtklei

SCOPe Domain Coordinates for d2hlfd1:

Click to download the PDB-style file with coordinates for d2hlfd1.
(The format of our PDB-style files is described here.)

Timeline for d2hlfd1: