SCOPe 2.01: Domain d2hhfa_: 2hhf A:

Lineage for d2hhfa_ (2hhf A:)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.17: D-aminoacid aminotransferase-like PLP-dependent enzymes [56751] (1 superfamily)
   2 domains: (1) alpha+beta: beta3-alpha2-beta2; (2) alpha/beta, a part of its mixed sheet forms barrel: n=6, S=8

4. Superfamily e.17.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56752] (2 families)

5. Family e.17.1.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56753] (4 proteins)

6. Protein Branched-chain aminoacid aminotransferase [56757] (2 species)

7. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [64508] (9 PDB entries)

8. Domain d2hhfa_: 2hhf A: [136474]
   automated match to d1ekfa_
   complexed with epe, plp

Details for d2hhfa_

PDB Entry: 2hhf, 1.8 Å

PDB Description: x-ray crystal structure of oxidized human mitochondrial branched chain aminotransferase (hbcatm)

PDB Compounds: (A:) Branched-chain-amino-acid aminotransferase, mitochondrial

SCOPe Domain Sequences for d2hhfa_:

Sequence, based on SEQRES records:

>d2hhfa_ e.17.1.1 (A:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
asssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpfqnlt
lhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellec
irrlievdkdwvpdaagtslyvrpvlignepslgvsqprrallfvilcpvgayfpggsvt
pvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgt
mnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllral
eegrvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahe
wmfpv

Sequence, based on observed residues (ATOM records):

>d2hhfa_ e.17.1.1 (A:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
asssfkaadlqlemttftdhmlmvewndkgwgqpriqpfqnltlhpassslhyslqlfeg
mkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrlievdkdwvpdaag
tslyvrpvlignepslgvsqprrallfvilcpvgayfpggsvtpvslladpafirawvgg
vgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifvywthedgvlelv
tpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrvrevfgsgtacqv
cpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv

Timeline for d2hhfa_:

• d2hhfa_ first appeared in SCOP 1.73, called d2hhfa1
  
• d2hhfa_ was called d2hhfa1 in SCOP 1.75
  
• d2hhfa_ appears in SCOPe 2.02
  
• d2hhfa_ appears in the current release, SCOPe 2.08