SCOPe 2.08: Domain d2hh5b_: 2hh5 B:

Lineage for d2hh5b_ (2hh5 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein (Pro)cathepsin S [82566] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82567] (28 PDB entries)

8. Domain d2hh5b_: 2hh5 B: [136469]
   automated match to d1ms6a_
   complexed with cl, gnq, zn

Details for d2hh5b_

PDB Entry: 2hh5, 1.8 Å

PDB Description: Crystal Structure of Cathepsin S in complex with a Zinc mediated non-covalent arylaminoethyl amide

PDB Compounds: (B:) cathepsin S

SCOPe Domain Sequences for d2hh5b_:

Sequence; same for both SEQRES and ATOM records:

>d2hh5b_ d.3.1.1 (B:) (Pro)cathepsin S {Human (Homo sapiens) [TaxId: 9606]}
lpdsvdwrekgcvtevkyqgscgacwafsavgaleaqlklktgklvslsaqnlvdcstek
ygnkgcnggfmttafqyiidnkgidsdasypykamdqkcqydskyraatcskytelpygr
edvlkeavankgpvsvgvdarhpsfflyrsgvyyepsctqnvnhgvlvvgygdlngkeyw
lvknswghnfgeegyirmarnkgnhcgiasfpsypei

Timeline for d2hh5b_:

• d2hh5b_ first appeared in SCOP 1.73, called d2hh5b1
  
• d2hh5b_ appears in SCOPe 2.07