Lineage for d2hfja1 (2hfj A:9-291)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 706658Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 706659Superfamily c.69.1: alpha/beta-Hydrolases [53474] (35 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9
  5. 707398Family c.69.1.22: Thioesterase domain of polypeptide, polyketide and fatty acid synthases [69584] (4 proteins)
    Pfam PF00975
  6. 707410Protein Picromycin polyketide synthase [82513] (1 species)
  7. 707411Species Streptomyces venezuelae [TaxId:54571] [82514] (6 PDB entries)
  8. 707416Domain d2hfja1: 2hfj A:9-291 [136386]
    automatically matched to d1mn6b_
    complexed with dms, mg, so4, yml

Details for d2hfja1

PDB Entry: 2hfj (more details), 1.95 Å

PDB Description: pikromycin thioesterase with covalent pentaketide affinity label
PDB Compounds: (A:) Type I polyketide synthase PikAIV

SCOP Domain Sequences for d2hfja1:

Sequence, based on SEQRES records: (download)

>d2hfja1 c.69.1.22 (A:9-291) Picromycin polyketide synthase {Streptomyces venezuelae [TaxId: 54571]}
agmfralfrqaveddrygefldvlaeasafrpqfaspeacserldpvllaggptdraegr
avlvgctgtaanggpheflrlstsfqeerdflavplpgygtgtgtgtallpadldtalda
qarailraagdapvvllghsggallahelafrlerahgappagivlvdpyppghqepiev
wsrqlgeglfagelepmsdarllamgryarflagprpgrssapvllvraseplgdwqeer
gdwrahwdlphtvadvpgdhftmmrdhapavaeavlswldaie

Sequence, based on observed residues (ATOM records): (download)

>d2hfja1 c.69.1.22 (A:9-291) Picromycin polyketide synthase {Streptomyces venezuelae [TaxId: 54571]}
agmfralfrqaveddrygefldvlaeasafrpqfaspeacserldpvllaggptdegrav
lvgctgtaanggpheflrlstsfqeerdflavplpgygtggtallpadldtaldaqarai
lraagdapvvllghsggallahelafrlerahgappagivlvdpyppghqepievwsrql
geglfagelepmsdarllamgryarflagprpgrssapvllvraseplgdwqeergdwra
hwdlphtvadvpgdhftmmrdhapavaeavlswldaie

SCOP Domain Coordinates for d2hfja1:

Click to download the PDB-style file with coordinates for d2hfja1.
(The format of our PDB-style files is described here.)

Timeline for d2hfja1: