SCOPe 2.07: Domain d2hdjb_: 2hdj B:

Lineage for d2hdjb_ (2hdj B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families)

5. Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
   Common fold covers whole protein structure

6. Protein 3-alpha-hydroxysteroid dehydrogenase [51439] (2 species)

7. Species Human (Homo sapiens), type III [TaxId:9606] [69383] (16 PDB entries)
   bile acid binding protein

8. Domain d2hdjb_: 2hdj B: [136344]
   automated match to d1j96a_
   complexed with edo, ndp, so4

Details for d2hdjb_

PDB Entry: 2hdj, 2 Å

PDB Description: Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H)

PDB Compounds: (B:) Aldo-keto reductase family 1 member C2

SCOPe Domain Sequences for d2hdjb_:

Sequence; same for both SEQRES and ATOM records:

>d2hdjb_ c.1.7.1 (B:) 3-alpha-hydroxysteroid dehydrogenase {Human (Homo sapiens), type III [TaxId: 9606]}
dskyqcvklndghfmpvlgfgtyapaevpkskaleavklaieagfhhidsahvynneeqv
glairskiadgsvkredifytsklwsnshrpelvrpalerslknlqldyvdlylihfpvs
vkpgeevipkdengkilfdtvdlcatweamekckdaglaksigvsnfnhrllemilnkpg
lkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpvl
calakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidglnr
nvryltldifagppnypfsdey

Timeline for d2hdjb_:

• d2hdjb_ first appeared in SCOP 1.73, called d2hdjb1
  
• d2hdjb_ appears in SCOPe 2.06
  
• d2hdjb_ appears in the current release, SCOPe 2.08