Lineage for d2hd1b1 (2hd1 B:181-506)

  1. Root: SCOP 1.75
  2. 758332Class a: All alpha proteins [46456] (284 folds)
  3. 780219Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 780220Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families) (S)
  5. 780284Family a.211.1.2: PDEase [48548] (6 proteins)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 780424Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (1 species)
  7. 780425Species Human (Homo sapiens) [TaxId:9606] [109943] (7 PDB entries)
    Uniprot O76083 241-566
  8. 780433Domain d2hd1b1: 2hd1 B:181-506 [136339]
    automatically matched to d1tbma_
    complexed with ibm, mg, zn

Details for d2hd1b1

PDB Entry: 2hd1 (more details), 2.23 Å

PDB Description: Crystal structure of PDE9 in complex with IBMX
PDB Compounds: (B:) Phosphodiesterase 9A

SCOP Domain Sequences for d2hd1b1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hd1b1 a.211.1.2 (B:181-506) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens) [TaxId: 9606]}
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk

SCOP Domain Coordinates for d2hd1b1:

Click to download the PDB-style file with coordinates for d2hd1b1.
(The format of our PDB-style files is described here.)

Timeline for d2hd1b1: