SCOPe 2.05: Domain d2h85a1: 2h85 A:1-190

Lineage for d2h85a1 (2h85 A:1-190)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.48: Nsp15 N-terminal domain-like [142625] (1 protein)
   rudiment methyltransferase fold that probably has lost the enzymatic activity; contains extra N-terminal alpha+beta subdomain

6. Protein Nsp15 [142626] (2 species)

7. Species SARS coronavirus [TaxId:227859] [142628] (3 PDB entries)
   Uniprot Q6VA80 6619-6774

8. Domain d2h85a1: 2h85 A:1-190 [136233]
   Other proteins in same PDB: d2h85a2

Details for d2h85a1

PDB Entry: 2h85, 2.6 Å

PDB Description: crystal structure of nsp 15 from sars

PDB Compounds: (A:) Putative orf1ab polyprotein

SCOPe Domain Sequences for d2h85a1:

Sequence; same for both SEQRES and ATOM records:

>d2h85a1 c.66.1.48 (A:1-190) Nsp15 {SARS coronavirus [TaxId: 227859]}
slenvaynvvnkghfdghageapvsiinnavytkvdgidveifenkttlpvnvafelwak
rnikpvpeikilnnlgvdiaantviwdykreapahvstigvctmtdiakkptesacsslt
vlfdgrvegqvdlfrnarngvlitegsvkgltpskgpaqasvngvtligesvktqfnyfk
kvdgiiqqlp

Timeline for d2h85a1:

• d2h85a1 first appeared in SCOP 1.73
  
• d2h85a1 appears in SCOPe 2.04
  
• d2h85a1 appears in SCOPe 2.06
  
• d2h85a1 appears in the current release, SCOPe 2.08