SCOPe 2.08: Domain d2h6ia1: 2h6i A:55-369

Lineage for d2h6ia1 (2h6i A:55-369)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (13 PDB entries)
   Uniprot P49354

8. Domain d2h6ia1: 2h6i A:55-369 [136189]
   Other proteins in same PDB: d2h6ib1
   automatically matched to d1s63a_
   complexed with ger, zn; mutant

Details for d2h6ia1

PDB Entry: 2h6i, 3 Å

PDB Description: w102t/y365f protein farnesyltransferase double mutant complexed with a geranylgeranylated ddptasacvls peptide product at 3.0a

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOPe Domain Sequences for d2h6ia1:

Sequence; same for both SEQRES and ATOM records:

>d2h6ia1 a.118.6.1 (A:55-369) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d2h6ia1:

• d2h6ia1 first appeared in SCOP 1.73
  
• d2h6ia1 appears in SCOPe 2.07