SCOPe 2.01: Domain d2h6ha1: 2h6h A:55-369

Lineage for d2h6ha1 (2h6h A:55-369)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (20 PDB entries)
   Uniprot P49354

8. Domain d2h6ha1: 2h6h A:55-369 [136188]
   Other proteins in same PDB: d2h6hb1
   automatically matched to d1s63a_
   complexed with acy, far, suc, zn; mutant

Details for d2h6ha1

PDB Entry: 2h6h, 1.8 Å

PDB Description: y365f protein farnesyltransferase mutant complexed with a farnesylated ddptasacvls peptide product at 1.8a

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOPe Domain Sequences for d2h6ha1:

Sequence; same for both SEQRES and ATOM records:

>d2h6ha1 a.118.6.1 (A:55-369) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d2h6ha1:

• d2h6ha1 first appeared in SCOP 1.73
  
• d2h6ha1 appears in SCOP 1.75
  
• d2h6ha1 appears in SCOPe 2.02
  
• d2h6ha1 appears in the current release, SCOPe 2.08