SCOPe 2.01: Domain d2h62b_: 2h62 B:

Lineage for d2h62b_ (2h62 B:)

1. Root: SCOPe 2.01

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57517] (10 PDB entries)

8. Domain d2h62b_: 2h62 B: [136178]
   Other proteins in same PDB: d2h62c1, d2h62d_
   automated match to d3bmpa_

Details for d2h62b_

PDB Entry: 2h62, 1.85 Å

PDB Description: Crystal structure of a ternary ligand-receptor complex of BMP-2

PDB Compounds: (B:) Bone morphogenetic protein 2

SCOPe Domain Sequences for d2h62b_:

Sequence; same for both SEQRES and ATOM records:

>d2h62b_ g.17.1.2 (B:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Timeline for d2h62b_:

• d2h62b_ first appeared in SCOP 1.73, called d2h62b1
  
• d2h62b_ was called d2h62b1 in SCOP 1.75
  
• d2h62b_ appears in SCOPe 2.02
  
• d2h62b_ appears in the current release, SCOPe 2.08