SCOP 1.75: Domain d2h5sa1: 2h5s A:26-292

Lineage for d2h5sa1 (2h5s A:26-292)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (3 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (18 proteins)

6. Protein beta-Lactamase, class A [56606] (15 species)

7. Species Klebsiella pneumoniae, SHV-1 [TaxId:573] [56609] (15 PDB entries)
   Uniprot Q5PSW7
   Uniprot P14557 22-286
   inhibited by tazobactam
   Uniprot Q5PSW7 ! Uniprot P14557 22-286

8. Domain d2h5sa1: 2h5s A:26-292 [136168]
   automatically matched to d1onga_
   complexed with ma4, sa2

Details for d2h5sa1

PDB Entry: 2h5s, 1.28 Å

PDB Description: sa2-13 penam sulfone complexed to wt shv-1 beta-lactamase

PDB Compounds: (A:) SHV-1 beta-lactamase

SCOP Domain Sequences for d2h5sa1:

Sequence; same for both SEQRES and ATOM records:

>d2h5sa1 e.3.1.1 (A:26-292) beta-Lactamase, class A {Klebsiella pneumoniae, SHV-1 [TaxId: 573]}
spqpleqiklsesqlsgrvgmiemdlasgrtltawraderfpmmstfkvvlcgavlarvd
agdeqlerkihyrqqdlvdyspvsekhladgmtvgelcaaaitmsdnsaanlllatvggp
agltaflrqigdnvtrldrwetelnealpgdardtttpasmaatlrklltsqrlsarsqr
qllqwmvddrvagplirsvlpagwfiadktgagergargivallgpnnkaerivviylrd
tpasmaernqqiagigaaliehwqr

Timeline for d2h5sa1:

• d2h5sa1 first appeared in SCOP 1.73
  
• d2h5sa1 is called d2h5sa_ in SCOPe 2.01
  
• d2h5sa1 appears in the current release, SCOPe 2.08, called d2h5sa_