Lineage for d2h46e1 (2h46 E:55-152)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 729699Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. 729700Superfamily d.93.1: SH2 domain [55550] (1 family) (S)
  5. 729701Family d.93.1.1: SH2 domain [55551] (32 proteins)
    Pfam PF00017
  6. 729836Protein Growth factor receptor-bound protein 2 (GRB2) [55563] (1 species)
  7. 729837Species Human (Homo sapiens) [TaxId:9606] [55564] (20 PDB entries)
  8. 729844Domain d2h46e1: 2h46 E:55-152 [136070]
    automatically matched to d1fhs__
    complexed with gol

Details for d2h46e1

PDB Entry: 2h46 (more details), 1.9 Å

PDB Description: native domain-swapped dimer crystal structure of the grb2 sh2 domain
PDB Compounds: (E:) Growth Receptor Binding Protein 2

SCOP Domain Sequences for d2h46e1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2h46e1 d.93.1.1 (E:55-152) Growth factor receptor-bound protein 2 (GRB2) {Human (Homo sapiens) [TaxId: 9606]}
mkphpwffgkiprakaeemlskqrhdgafliresesapgdfslsvkfgndvqhfkvlrdg
agkyflwvvkfnslnelvdyhrstsvsrnqqiflrdie

SCOP Domain Coordinates for d2h46e1:

Click to download the PDB-style file with coordinates for d2h46e1.
(The format of our PDB-style files is described here.)

Timeline for d2h46e1: