SCOPe 2.05: Domain d2gyyd1: 2gyy D:3-127,D:330-350

Lineage for d2gyyd1 (2gyy D:3-127,D:330-350)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

7. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (18 PDB entries)
   Uniprot Q8DQ00 2-127,330-357

8. Domain d2gyyd1: 2gyy D:3-127,D:330-350 [135885]
   Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
   automated match to d2gyya1

Details for d2gyyd1

PDB Entry: 2gyy, 2.1 Å

PDB Description: Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae

PDB Compounds: (D:) Aspartate beta-semialdehyde dehydrogenase

SCOPe Domain Sequences for d2gyyd1:

Sequence, based on SEQRES records:

>d2gyyd1 c.2.1.3 (D:3-127,D:330-350) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}
ytvavvgatgavgaqmikmleestlpidkirylasarsagkslkfkdqditieettetaf
egvdialfsagsstsakyapyavkagvvvvdntsyfrqnpdvplvvpevnahaldahngi
iacpnXaawnsvqiaetlherglvrpt

Sequence, based on observed residues (ATOM records):

>d2gyyd1 c.2.1.3 (D:3-127,D:330-350) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}
ytvavvgatgavgaqmikmleestlpidkirylgkslkfkdqditieettetafegvdia
lfsagsstsakyapyavkagvvvvdntsyfrqnpdvplvvpevnahaldahngiiacpnX
aawnsvqiaetlherglvrpt

Timeline for d2gyyd1:

• d2gyyd1 first appeared in SCOP 1.73
  
• d2gyyd1 appears in SCOPe 2.04
  
• d2gyyd1 appears in SCOPe 2.06
  
• d2gyyd1 appears in the current release, SCOPe 2.08