SCOPe 2.05: Domain d2gyyb1: 2gyy B:2-127,B:330-356

Lineage for d2gyyb1 (2gyy B:2-127,B:330-356)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
   family members also share a common alpha+beta fold in C-terminal domain

6. Protein Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)

7. Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (18 PDB entries)
   Uniprot Q8DQ00 2-127,330-357

8. Domain d2gyyb1: 2gyy B:2-127,B:330-356 [135881]
   Other proteins in same PDB: d2gyya2, d2gyyb2, d2gyyc2, d2gyyd2
   automated match to d2gyya1

Details for d2gyyb1

PDB Entry: 2gyy, 2.1 Å

PDB Description: Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae

PDB Compounds: (B:) Aspartate beta-semialdehyde dehydrogenase

SCOPe Domain Sequences for d2gyyb1:

Sequence, based on SEQRES records:

>d2gyyb1 c.2.1.3 (B:2-127,B:330-356) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}
gytvavvgatgavgaqmikmleestlpidkirylasarsagkslkfkdqditieetteta
fegvdialfsagsstsakyapyavkagvvvvdntsyfrqnpdvplvvpevnahaldahng
iiacpnXaawnsvqiaetlherglvrptaelkfe

Sequence, based on observed residues (ATOM records):

>d2gyyb1 c.2.1.3 (B:2-127,B:330-356) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}
gytvavvgatgaqmikmleestlpidkiryldqditieettetafegvdialfsagssts
akyapyavkagvvvvdntsyfrqnpdvplvvpevnahaldahngiiacpnXaawnsvqia
etlherglvrptaelkfe

Timeline for d2gyyb1:

• d2gyyb1 first appeared in SCOP 1.73
  
• d2gyyb1 appears in SCOPe 2.04
  
• d2gyyb1 appears in SCOPe 2.06
  
• d2gyyb1 appears in the current release, SCOPe 2.08