SCOPe 2.08: Domain d2gvca1: 2gvc A:3-180,A:288-444

Lineage for d2gvca1 (2gvc A:3-180,A:288-444)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

6. Protein Flavin-dependent monoxygenase SPBP16F5.08c, N- and C-terminal domain [418940] (1 species)

7. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [419392] (3 PDB entries)
   Uniprot Q9HFE4

8. Domain d2gvca1: 2gvc A:3-180,A:288-444 [135763]
   Other proteins in same PDB: d2gvca2, d2gvcb2, d2gvcd2, d2gvce2
   automatically matched to d1vqwa1
   complexed with fad, gol, mmz, peo
   has additional insertions and/or extensions that are not grouped together

Details for d2gvca1

PDB Entry: 2gvc, 2.22 Å

PDB Description: crystal structure of flavin-containing monooxygenase (fmo)from s.pombe and substrate (methimazole) complex

PDB Compounds: (A:) monooxygenase

SCOPe Domain Sequences for d2gvca1:

Sequence; same for both SEQRES and ATOM records:

>d2gvca1 c.3.1.5 (A:3-180,A:288-444) Flavin-dependent monoxygenase SPBP16F5.08c, N- and C-terminal domain {Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]}
lptirkiaiigagpsglvtakallaekafdqvtlferrgspggvwnytstlsnklpvpst
npilttepivgpaalpvypsplyrdlqtntpielmgycdqsfkpqtlqfphrhtiqeyqr
iyaqpllpfiklatdvldiekkdgswvvtykgtkagspiskdifdavsicnghyevpyXt
gylysvpfpslaklkspetkliddgshvhnvyqhifyipdptlafvglalhvvpfptsqa
qaaflarvwsgrlklpskeeqlkwqdelmfslsgannmyhsldypkdatyinklhdwckq
atpvleeefpspywgekersirenmwsirakffgie

Timeline for d2gvca1:

• d2gvca1 first appeared in SCOP 1.73
  
• d2gvca1 appears in SCOPe 2.07