Lineage for d2gtia2 (2gti A:217-369)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 741509Fold d.294: EndoU-like [142876] (1 superfamily)
    comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (scop_cf 54075)
  4. 741510Superfamily d.294.1: EndoU-like [142877] (2 families) (S)
    similarity to the RNase A-like superfamily (scop_sf 54076) extends to the active site location and architecture; the two structural cores of the RNase A and EndoU superfamilies are interrelated by a topological permutation - transposition of two pereferial beta-strands, suggesting possible distant homology of the two superfamilies (and their unification in a hyperfamily)
  5. 741517Family d.294.1.2: Nsp15 C-terminal domain-like [142881] (1 protein)
    PfamB 001946
  6. 741518Protein Nsp15, C-terminal domain [142882] (2 species)
  7. 741519Species Murine hepatitis virus, MHV [TaxId:11138] [142884] (2 PDB entries)
  8. 741520Domain d2gtia2: 2gti A:217-369 [135653]
    Other proteins in same PDB: d2gtia1
    complexed with gol, so4; mutant

Details for d2gtia2

PDB Entry: 2gti (more details), 2.15 Å

PDB Description: mutation of mhv coronavirus non-structural protein nsp15 (f307l)
PDB Compounds: (A:) Replicase polyprotein 1ab

SCOP Domain Sequences for d2gtia2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2gtia2 d.294.1.2 (A:217-369) Nsp15, C-terminal domain {Murine hepatitis virus, MHV [TaxId: 11138]}

SCOP Domain Coordinates for d2gtia2:

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Timeline for d2gtia2:

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