SCOPe 2.01: Domain d2gt9a2: 2gt9 A:1-181

Lineage for d2gt9a2 (2gt9 A:1-181)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
   dimeric

4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (1 family)

5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

6. Protein Class I MHC, alpha-1 and alpha-2 domains [54468] (27 species)

7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (76 PDB entries)
   Uniprot P01892 25-298

8. Domain d2gt9a2: 2gt9 A:1-181 [135625]
   Other proteins in same PDB: d2gt9a1, d2gt9b_, d2gt9d1, d2gt9e_
   automatically matched to d1akja2
   complexed with gol, na

Details for d2gt9a2

PDB Entry: 2gt9, 1.75 Å

PDB Description: Human Class I MHC HLA-A2 in complex with the decameric Melan-A/MART-1(26-35) peptide

PDB Compounds: (A:) hla class I histocompatibility antigen

SCOPe Domain Sequences for d2gt9a2:

Sequence; same for both SEQRES and ATOM records:

>d2gt9a2 d.19.1.1 (A:1-181) Class I MHC, alpha-1 and alpha-2 domains {Human (Homo sapiens), HLA-A2.1 [TaxId: 9606]}
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
r

Timeline for d2gt9a2:

• d2gt9a2 first appeared in SCOP 1.73
  
• d2gt9a2 appears in SCOP 1.75
  
• d2gt9a2 appears in SCOPe 2.02
  
• d2gt9a2 appears in the current release, SCOPe 2.08