SCOP 1.73: Domain d2good1: 2goo D:12-114

Lineage for d2good1 (2goo D:12-114)

1. Root: SCOP 1.73

2. Class g: Small proteins [56992] (85 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (7 proteins)

6. Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57517] (6 PDB entries)

8. Domain d2good1: 2goo D:12-114 [135444]
   Other proteins in same PDB: d2goob1, d2gooc1, d2gooe1, d2goof1
   automatically matched to d3bmpa_
   complexed with ndg

Details for d2good1

PDB Entry: 2goo, 2.2 Å

PDB Description: ternary complex of bmp-2 bound to bmpr-ia-ecd and actrii-ecd

PDB Compounds: (D:) Bone morphogenetic protein 2

SCOP Domain Sequences for d2good1:

Sequence; same for both SEQRES and ATOM records:

>d2good1 g.17.1.2 (D:12-114) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Timeline for d2good1:

• d2good1 is new in SCOP 1.73
  
• d2good1 appears in SCOP 1.75
  
• d2good1 appears in the current release, SCOPe 2.08, called d2good_