SCOPe 2.06: Domain d2gmva1: 2gmv A:260-622

Lineage for d2gmva1 (2gmv A:260-622)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.91: PEP carboxykinase-like [53794] (1 superfamily)
   contains a P-loop NTP-binding motif; mixed beta-sheet folds into a barrel-like structure with helices packed on one side

4. Superfamily c.91.1: PEP carboxykinase-like [53795] (3 families)

5. Family c.91.1.1: PEP carboxykinase C-terminal domain [53796] (3 proteins)

6. Protein Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) [69612] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69613] (7 PDB entries)

8. Domain d2gmva1: 2gmv A:260-622 [135394]
   Other proteins in same PDB: d2gmva2, d2gmvb2
   automated match to d1khba1
   complexed with mn, pep, un8

Details for d2gmva1

PDB Entry: 2gmv, 2.3 Å

PDB Description: pepck complex with a gtp-competitive inhibitor

PDB Compounds: (A:) Phosphoenolpyruvate carboxykinase, cytosolic

SCOPe Domain Sequences for d2gmva1:

Sequence, based on SEQRES records:

>d2gmva1 c.91.1.1 (A:260-622) Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) {Human (Homo sapiens) [TaxId: 9606]}
wlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvgddiawmkfda
qghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvywegideplas
gvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpiegiifggrrpa
gvplvyealswqhgvfvgaamrseataaaehkgkiimhdpfamrpffgynfgkylahwls
maqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgkastkltpigyip
kedalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqri
sqm

Sequence, based on observed residues (ATOM records):

>d2gmva1 c.91.1.1 (A:260-622) Cytosolic phosphoenolpyruvate carboxykinase (GTP-hydrolyzing) {Human (Homo sapiens) [TaxId: 9606]}
wlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvgddiawmkfda
qghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvywegideplas
gvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpiegiifggrrpa
gvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahwlsmaqhpaak
lpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgtkltpigyipkedalnlkglg
hinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqrisqm

Timeline for d2gmva1:

• d2gmva1 first appeared in SCOP 1.73
  
• d2gmva1 appears in SCOPe 2.05
  
• d2gmva1 appears in SCOPe 2.07
  
• d2gmva1 appears in the current release, SCOPe 2.08