SCOP 1.75: Domain d2gkla1: 2gkl A:41-305

Lineage for d2gkla1 (2gkl A:41-305)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

4. Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (14 families)

5. Family d.157.1.1: Zn metallo-beta-lactamase [56282] (1 protein)

6. Protein Zn metallo-beta-lactamase [56283] (10 species)

7. Species Aeromonas hydrophila, CphA [TaxId:644] [118144] (5 PDB entries)
   Uniprot P26918 28-252

8. Domain d2gkla1: 2gkl A:41-305 [135333]
   automatically matched to d1x8ga_
   complexed with gol, pd2, zn

Details for d2gkla1

PDB Entry: 2gkl, 1.86 Å

PDB Description: Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate

PDB Compounds: (A:) Beta-lactamase

SCOP Domain Sequences for d2gkla1:

Sequence; same for both SEQRES and ATOM records:

>d2gkla1 d.157.1.1 (A:41-305) Zn metallo-beta-lactamase {Aeromonas hydrophila, CphA [TaxId: 644]}
agmsltqvsgpvyvvednyyvqensmvyfgakgvtvvgatwtpdtarelhklikrvsrkp
vlevintnyhtdraggnaywksigakvvstrqtrdlmksdwaeivaftrkglpeypdlpl
vlpnvvhdgdftlqegkvrafyagpahtpdgifvyfpdeqvlygncilkeklgnlsfadv
kaypqtlerlkamklpiktvigghdsplhgpelidhyealikaap

Timeline for d2gkla1:

• d2gkla1 first appeared in SCOP 1.73
  
• d2gkla1 is called d2gkla_ in SCOPe 2.01
  
• d2gkla1 appears in the current release, SCOPe 2.08, called d2gkla_