SCOP 1.75: Domain d2gjxg1: 2gjx G:200-552

Lineage for d2gjxg1 (2gjx G:200-552)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (14 families)

5. Family c.1.8.6: beta-N-acetylhexosaminidase catalytic domain [51550] (5 proteins)
   Glycosyl hydrolase family 20, GH20

6. Protein beta-hexosaminidase B [89486] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89487] (6 PDB entries)

8. Domain d2gjxg1: 2gjx G:200-552 [135317]
   Other proteins in same PDB: d2gjxa1, d2gjxa2, d2gjxb2, d2gjxc2, d2gjxd1, d2gjxd2, d2gjxe1, d2gjxe2, d2gjxf2, d2gjxg2, d2gjxh1, d2gjxh2
   automatically matched to d1o7aa1
   complexed with bma, nag, ndg, so4

Details for d2gjxg1

PDB Entry: 2gjx, 2.8 Å

PDB Description: crystallographic structure of human beta-hexosaminidase a

PDB Compounds: (G:) beta-hexosaminidase beta chain

SCOP Domain Sequences for d2gjxg1:

Sequence, based on SEQRES records:

>d2gjxg1 c.1.8.6 (G:200-552) beta-hexosaminidase B {Human (Homo sapiens) [TaxId: 9606]}
fshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqsitfpelsnkgs
yslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltpcysrqnkldsf
gpinptlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmrqkgfgtd
fkklesfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypeelsrvtas
gfpvilsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgeyvdatnlt
prlwprasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycn

Sequence, based on observed residues (ATOM records):

>d2gjxg1 c.1.8.6 (G:200-552) beta-hexosaminidase B {Human (Homo sapiens) [TaxId: 9606]}
fshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqsitfpelsnkgs
yslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltpcysdsfgpinp
tlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmrqkgfgtdfkkle
sfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypeelsrvtasgfpvi
lsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgeyvdatnltprlwp
rasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycn

Timeline for d2gjxg1:

• d2gjxg1 first appeared in SCOP 1.73
  
• d2gjxg1 appears in SCOPe 2.01
  
• d2gjxg1 appears in the current release, SCOPe 2.08