SCOPe 2.08: Domain d2giua_: 2giu A:

Lineage for d2giua_ (2giu A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor beta [48521] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48522] (27 PDB entries)

8. Domain d2giua_: 2giu A: [135252]
   automated match to d1qkma_
   complexed with fbr

Details for d2giua_

PDB Entry: 2giu, 2.2 Å

PDB Description: human estrogen receptor beta ligand-binding domain in complex with compound 45

PDB Compounds: (A:) Estrogen receptor beta

SCOPe Domain Sequences for d2giua_:

Sequence, based on SEQRES records:

>d2giua_ a.123.1.1 (A:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
ldalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgf
velslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdm
llattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvw
viaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlnahv
l

Sequence, based on observed residues (ATOM records):

>d2giua_ a.123.1.1 (A:) Estrogen receptor beta {Human (Homo sapiens) [TaxId: 9606]}
ldalspeqlvltlleaepphvlisrpasmmmsltkladkelvhmiswakkipgfvelslf
dqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcegileifdmllattsr
frelklqhkeylcvkamillnssmyplvadssrklahllnavtdalvwviaksgissqqq
smrlanllmllshvrhasnkgmehllnmvvpvydlllemlnahvl

Timeline for d2giua_:

• d2giua_ first appeared in SCOP 1.73, called d2giua1
  
• d2giua_ appears in SCOPe 2.07