SCOPe 2.01: Domain d2gfha1: 2gfh A:1-247

Lineage for d2gfha1 (2gfh A:1-247)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.6: beta-Phosphoglucomutase-like [75173] (10 proteins)
   the insertion subdomain is a 4-helical bundle

6. Protein N-acylneuraminate-9-phosphatase NANP [142137] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [142138] (1 PDB entry)
   Uniprot Q9CPT3 1-247

8. Domain d2gfha1: 2gfh A:1-247 [135096]
   complexed with cl, edo, na, po4

Details for d2gfha1

PDB Entry: 2gfh, 1.9 Å

PDB Description: Crystal structure of a n-acetylneuraminic acid phosphatase (nanp) from mus musculus at 1.90 A resolution

PDB Compounds: (A:) haloacid dehalogenase-like hydrolase domain containing 4

SCOPe Domain Sequences for d2gfha1:

Sequence, based on SEQRES records:

>d2gfha1 c.108.1.6 (A:1-247) N-acylneuraminate-9-phosphatase NANP {Mouse (Mus musculus) [TaxId: 10090]}
mglsrvravffdldntlidtagasrrgmlevikllqskyhykeeaeiicdkvqvklskec
fhpystcitdvrtshweeaiqetkggadnrklaeecyflwkstrlqhmiladdvkamlte
lrkevrlllltngdrqtqrekieacacqsyfdaiviggeqkeekpapsifyhccdllgvq
pgdcvmvgdtletdiqgglnaglkatvwinksgrvpltsspmphymvssvlelpallqsi
dckvsms

Sequence, based on observed residues (ATOM records):

>d2gfha1 c.108.1.6 (A:1-247) N-acylneuraminate-9-phosphatase NANP {Mouse (Mus musculus) [TaxId: 10090]}
mglsrvravffdldntlidtagasrrgmlevikllqskyhykeeaeiicdkvqvklskec
fhcitdvrtshweeaiqetkggadnrklaeecyflwkstrlqhmiladdvkamltelrke
vrlllltngdrqtqrekieacacqsyfdaiviggeqkeekpapsifyhccdllgvqpgdc
vmvgdtletdiqgglnaglkatvwinksgrvpltsspmphymvssvlelpallqsidckv
sms

Timeline for d2gfha1:

• d2gfha1 first appeared in SCOP 1.73
  
• d2gfha1 appears in SCOP 1.75
  
• d2gfha1 appears in SCOPe 2.02
  
• d2gfha1 appears in the current release, SCOPe 2.08