SCOPe 2.07: Domain d2gd6d_: 2gd6 D:

Lineage for d2gd6d_ (2gd6 D:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.123: CoA-transferase family III (CaiB/BaiF) [89795] (1 superfamily)
   consist of two different alpha/beta domains; N-terminal domain has a SurE-like topology with a left-handed beta-alpha-beta unit

4. Superfamily c.123.1: CoA-transferase family III (CaiB/BaiF) [89796] (2 families)

5. Family c.123.1.1: CoA-transferase family III (CaiB/BaiF) [89797] (5 proteins)
   forms interlocked homodimer of two ring-like subunits

6. Protein 2-methylacyl-CoA racemase Mcr [142827] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [142828] (7 PDB entries)
   Uniprot O06543 2-360

8. Domain d2gd6d_: 2gd6 D: [135009]
   automated match to d1x74a1
   complexed with aco, gol

Details for d2gd6d_

PDB Entry: 2gd6, 2.3 Å

PDB Description: the 1,1-proton transfer reaction mechanism by alpha-methylacyl-coa racemase is catalyzed by an aspartate/histidine pair and involves a smooth, methionine-rich surface for binding the fatty acyl moiety

PDB Compounds: (D:) probable alpha-methylacyl-CoA racemase MCR

SCOPe Domain Sequences for d2gd6d_:

Sequence, based on SEQRES records:

>d2gd6d_ c.123.1.1 (D:) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtadl
ksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprs
qqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkg
qvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaie
pqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpv
lafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

Sequence, based on observed residues (ATOM records):

>d2gd6d_ c.123.1.1 (D:) 2-methylacyl-CoA racemase Mcr {Mycobacterium tuberculosis [TaxId: 1773]}
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

Timeline for d2gd6d_:

• d2gd6d_ first appeared in SCOP 1.73, called d2gd6d1
  
• d2gd6d_ appears in SCOPe 2.06
  
• d2gd6d_ appears in the current release, SCOPe 2.08