SCOP 1.73: Domain d2gafa1: 2gaf A:1-297

Lineage for d2gafa1 (2gaf A:1-297)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (52 families)

5. Family c.66.1.25: mRNA cap methylase [88785] (2 proteins)

6. Protein Polymerase regulatory subunit VP39 [53361] (1 species)

7. Species Vaccinia virus [TaxId:10245] [53362] (19 PDB entries)

8. Domain d2gafa1: 2gaf A:1-297 [134888]
   automatically matched to d1vpt__
   mutant

Details for d2gafa1

PDB Entry: 2gaf, 2.4 Å

PDB Description: crystal structure of the vaccinia polyadenylate polymerase heterodimer (apo form)

PDB Compounds: (A:) Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase

SCOP Domain Sequences for d2gafa1:

Sequence, based on SEQRES records:

>d2gafa1 c.66.1.25 (A:1-297) Polymerase regulatory subunit VP39 {Vaccinia virus [TaxId: 10245]}
mdvvsldkpfmyfeeidneldyepesanevakklpyqgqlklllgelfflsklqrhgild
gatvvyigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeey
lrsikkqlhpskiilisdvasaaggnepstadllsnyalqnvmisilnpvasslkwrcpf
pdqwikdfyiphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyyln
kivrnkvvvnfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

Sequence, based on observed residues (ATOM records):

>d2gafa1 c.66.1.25 (A:1-297) Polymerase regulatory subunit VP39 {Vaccinia virus [TaxId: 10245]}
mdvvsldkpfmyfeeidneldyepeskklpyqgqlklllgelfflsklqrhgildgatvv
yigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeeylrsik
kqlhpskiilisdvaspstadllsnyalqnvmisilnpvasslkwrcpfpdqwikdfyip
hgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyylnkivrnkvvvnf
dypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

Timeline for d2gafa1:

• d2gafa1 is new in SCOP 1.73
  
• d2gafa1 appears in SCOP 1.75
  
• d2gafa1 appears in the current release, SCOPe 2.08, called d2gafa_