SCOPe 2.08: Domain d2gafa_: 2gaf A:

Lineage for d2gafa_ (2gaf A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.25: mRNA cap methylase [88785] (4 proteins)

6. Protein automated matches [190302] (11 species)
   not a true protein

7. Species Vaccinia virus [TaxId:10245] [187111] (2 PDB entries)

8. Domain d2gafa_: 2gaf A: [134888]
   Other proteins in same PDB: d2gafd_
   automated match to d1vpt__

Details for d2gafa_

PDB Entry: 2gaf, 2.4 Å

PDB Description: crystal structure of the vaccinia polyadenylate polymerase heterodimer (apo form)

PDB Compounds: (A:) Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase

SCOPe Domain Sequences for d2gafa_:

Sequence, based on SEQRES records:

>d2gafa_ c.66.1.25 (A:) automated matches {Vaccinia virus [TaxId: 10245]}
mdvvsldkpfmyfeeidneldyepesanevakklpyqgqlklllgelfflsklqrhgild
gatvvyigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeey
lrsikkqlhpskiilisdvasaaggnepstadllsnyalqnvmisilnpvasslkwrcpf
pdqwikdfyiphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyyln
kivrnkvvvnfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

Sequence, based on observed residues (ATOM records):

>d2gafa_ c.66.1.25 (A:) automated matches {Vaccinia virus [TaxId: 10245]}
mdvvsldkpfmyfeeidneldyepeskklpyqgqlklllgelfflsklqrhgildgatvv
yigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeeylrsik
kqlhpskiilisdvaspstadllsnyalqnvmisilnpvasslkwrcpfpdqwikdfyip
hgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyylnkivrnkvvvnf
dypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

Timeline for d2gafa_:

• d2gafa_ first appeared in SCOP 1.73, called d2gafa1
  
• d2gafa_ appears in SCOPe 2.07